Alosetron not been shown to be effective in men with ibs. Alosetron is used to treat diarrhea and abdominal discomfort that occurs in some women with irritable bowel syndrome it works in a similar fashion as granisetron ondansetron and dolasetron that are used for preventing nausea and vomiting the discomfort and diarrhea of ibs is believed to be due to abnormal activity of the muscles of the intestines and or the nerves that control the muscles.
Lotronex is not a cure for irritable bowel syndrome.
Alosetron ibs. For a long time this was the only prescription medication approved to treat the condition. Alosetron is used to treat diarrhea pain cramps and the feeling of an urgent need to have bowel movements caused by irritable bowel syndrome ibs. After you stop taking this medicine your symptoms may return within 1 week.
Alosetron was withdrawn from the market in 2000 owing to the occurrence of serious life. This slows the movement of stools bowel movements through the intestines. Alosetron is used to treat severe chronic irritable bowel syndrome in women with diarrhea as the main symptom for at least 6 months.
News p 561 education and debate p 592 on 9 february 2000 alosetron marketed as lotronex by glaxosmithkline a type 3 serotonin 5 ht3 receptor antagonist was approved by the us food and drug administration fda for the treatment of patients with irritable bowel syndrome a benig though unpleasant disorder that affects one in five adults in the industrialised world 1 by november 2000 the. Medications specifically for ibs d. Alosetron blocks the action of a chemical called serotonin in the intestines.
Lotronex should be used only by women with severe irritable bowel syndrome and diarrhea as the main symptom. Alosetron is a serotonin 3 5 ht3 receptor antagonist used to treat diarrhea and abdominal discomfort that occurs in some women with irritable bowel syndrome. Alosetron lotronex glaxosmithkline is a potent and selective 5 ht 3 receptor antagonist approved by the fda for the treatment of women with diarrhoea predominant irritable bowel syndrome ibs in whom conventional therapy has failed.
It works in a similar fashion as granisetron kytril ondansetron zofran and dolasetron anzemet that are used to prevent nausea and vomiting. It was patented in 1987 and approved for medical use in 2002. So it s only to be used by women with severe ibs d whose symptoms.
Alosetron is given after other treatments have failed. It is currently marketed by prometheus laboratories inc. Alosetron lotronex can help ease stomach pain and slow your bowels to relieve diarrhea but there can be serious side effects.
A condition that causes stomach pain bloating constipation and diarrhea in women who have diarrhea as their main symptom and have not been helped by other treatments. Alosetron sold under the brand name lotronex among others is a 5 ht 3 antagonist used for the management of severe diarrhea predominant irritable bowel syndrome ibs in women only.
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